Details for gene set NCI_IL12-MEDIATED SIGNALING EVENTS[GSEA]

Table: GSEA Results Summary

Dataset	Set_02_BT_ATM_minus_versus_ATM_plus.phenotype_BT_ATM_minus_versus_ATM_plus.cls #BT_ATM_minus_versus_ATM_plus.phenotype_BT_ATM_minus_versus_ATM_plus.cls #BT_ATM_minus_versus_ATM_plus_repos
Phenotype	phenotype_BT_ATM_minus_versus_ATM_plus.cls#BT_ATM_minus_versus_ATM_plus_repos
Upregulated in class	ATM_plus
GeneSet	NCI_IL12-MEDIATED SIGNALING EVENTS
Enrichment Score (ES)	-0.47224554
Normalized Enrichment Score (NES)	-1.8047581
Nominal p-value	0.0
FDR q-value	0.24758966
FWER p-Value	0.693

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	LCK	1425396_a_at 1439145_at 1439146_s_at 1457917_at	50	2.528	0.0273	No
2	UBE2D3	1423112_at 1423113_a_at 1423114_at 1450858_a_at 1450859_s_at 1455479_a_at 1455480_s_at	77	2.421	0.0544	No
3	TGFB1	1420653_at 1445360_at	106	2.330	0.0803	No
4	SOCS1	1440047_at 1450446_a_at	198	1.904	0.0984	No
5	FBXW11	1425461_at 1425462_at 1437468_x_at 1438336_at 1443010_at 1447294_at 1457485_at	495	1.454	0.1019	No
6	SYK	1418261_at 1418262_at 1425797_a_at 1457239_at	557	1.383	0.1152	No
7	GZMA	1417898_a_at	624	1.325	0.1277	No
8	PIK3CA	1423144_at 1429434_at 1429435_x_at 1440054_at 1453134_at 1460326_at	854	1.165	0.1308	No
9	GZMB	1419060_at	1103	1.058	0.1318	No
10	PIK3R1	1425514_at 1425515_at 1438682_at 1444591_at 1451737_at	1613	0.946	0.1196	No
11	PIAS2	1419454_x_at 1426456_a_at 1428725_at	1840	0.892	0.1196	No
12	CHUK	1417091_at 1428210_s_at 1451383_a_at	2099	0.833	0.1176	No
13	IL2RA	1420691_at 1420692_at	2200	0.808	0.1224	No
14	MAP2K6	1426850_a_at 1459292_at	2630	0.715	0.1111	No
15	IL18R1	1421628_at	3371	0.583	0.0841	No
16	MAPK8	1420931_at 1420932_at 1437045_at 1440856_at 1457936_at	3414	0.576	0.0889	No
17	MAP2K3	1425456_a_at 1451714_a_at	4050	0.493	0.0656	No
18	ATM	1421205_at 1428830_at	4327	0.459	0.0583	No
19	CCR5	1422259_a_at 1422260_x_at 1424727_at	4701	0.420	0.0461	No
20	CYLD	1429617_at 1429618_at 1445213_at	5240	0.367	0.0258	No
21	IL4	1449864_at	5329	0.360	0.0259	No
22	CCL4	1421578_at	5373	0.355	0.0281	No
23	IL12RB2	1421623_at	5416	0.351	0.0303	No
24	CD28	1417597_at 1437025_at 1443703_at	5475	0.347	0.0317	No
25	MAPK9	1421876_at 1421877_at 1421878_at	5667	0.330	0.0268	No
26	CD8B	1426170_a_at 1446372_at 1448569_at 1458652_at	5674	0.329	0.0304	No
27	MALT1	1445068_at 1456126_at 1456429_at	6180	0.286	0.0106	No
28	XPO1	1418442_at 1418443_at 1448070_at	7177	0.210	-0.0326	No
29	BCL10	1418970_a_at 1418971_x_at 1418972_at 1443524_x_at	7261	0.204	-0.0340	No
30	CCL3	1419561_at	7670	0.176	-0.0506	No
31	JUN	1417409_at 1448694_at	8322	0.132	-0.0789	No
32	STAT4	1448713_at	8711	0.107	-0.0954	No
33	JAK1	1433803_at 1433804_at 1433805_at	9030	0.087	-0.1089	No
34	IL17A	1421672_at	9036	0.087	-0.1082	No
35	TNFRSF1A	1417291_at	9678	0.046	-0.1370	No
36	CD86	1420404_at 1449858_at	9864	0.034	-0.1450	No
37	FASLG	1418803_a_at 1449235_at	9986	0.027	-0.1503	No
38	IFNG	1425947_at	10234	0.011	-0.1615	No
39	PRKCA	1427562_a_at 1443069_at 1445028_at 1445395_at 1446598_at 1450945_at	10542	-0.008	-0.1754	No
40	CD3D	1422828_at	11144	-0.046	-0.2024	No
41	B2M	1427511_at 1449289_a_at 1452428_a_at	11355	-0.059	-0.2113	No
42	REL	1420710_at	11816	-0.088	-0.2314	No
43	TBX21	1449361_at	11939	-0.095	-0.2358	No
44	RAN	1443131_at 1446819_at 1447478_at 1460551_at	12231	-0.112	-0.2479	No
45	CD3G	1419178_at	12305	-0.117	-0.2498	No
46	SPHK2	1417431_a_at 1426230_at	12393	-0.124	-0.2524	No
47	CD3E	1422105_at 1445748_at	12436	-0.126	-0.2528	No
48	CD247	1420716_at 1426079_at 1426396_at 1428059_at 1428060_at 1438392_at 1452539_a_at	12463	-0.128	-0.2525	No
49	SRC	1423240_at 1450918_s_at	12489	-0.129	-0.2521	No
50	RIPK2	1421236_at 1450173_at	13249	-0.177	-0.2848	No
51	BIRC2	1418854_at	13634	-0.203	-0.3000	No
52	IL12RB1	1418166_at	13738	-0.210	-0.3023	No
53	IL6	1450297_at	13790	-0.213	-0.3021	No
54	IL18	1417932_at	13852	-0.218	-0.3024	No
55	STAT1	1420915_at 1440481_at 1450033_a_at 1450034_at	15109	-0.307	-0.3563	No
56	IL1B	1449399_a_at	15545	-0.340	-0.3723	No
57	CD80	1427717_at 1432826_a_at 1440592_at 1451950_a_at 1454372_at 1457952_at	16176	-0.391	-0.3965	No
58	EOMES	1426001_at 1435172_at	16289	-0.401	-0.3970	No
59	NFKBIA	1420088_at 1420089_at 1438157_s_at 1448306_at 1449731_s_at	16399	-0.411	-0.3972	No
60	MAP3K14	1422999_at 1434364_at	16681	-0.436	-0.4050	No
61	NFKB2	1425902_a_at 1429128_x_at	16780	-0.446	-0.4042	No
62	CD8A	1440164_x_at 1440811_x_at	16823	-0.450	-0.4009	No
63	IKBKB	1426207_at 1426333_a_at 1432275_at 1445141_at 1454184_a_at	16915	-0.460	-0.3997	No
64	STAT5A	1421469_a_at 1450259_a_at	16987	-0.467	-0.3975	No
65	STAT6	1421708_a_at 1426353_at	17837	-0.561	-0.4298	No
66	IL18RAP	1421291_at 1456545_at	17842	-0.562	-0.4234	No
67	JAK2	1421065_at 1421066_at	18068	-0.592	-0.4268	No
68	NFKB1	1427705_a_at 1442949_at	18289	-0.622	-0.4296	No
69	IL13	1420802_at	18588	-0.666	-0.4355	No
70	RELA	1419536_a_at	18597	-0.667	-0.4280	No
71	ERC1	1421501_a_at 1424247_at 1441493_at 1444356_at 1451279_at	18919	-0.717	-0.4343	No
72	TNF	1419607_at	19120	-0.750	-0.4347	No
73	GATA3	1448886_at	19704	-0.862	-0.4514	No
74	TYK2	1417306_at	20161	-0.971	-0.4609	Yes
75	IL12B	1419530_at 1449497_at	20298	-1.004	-0.4554	Yes
76	IL12A	1425454_a_at	20338	-1.011	-0.4454	Yes
77	TNFAIP3	1433699_at 1450829_at	20369	-1.017	-0.4348	Yes
78	IL2RB	1417546_at 1448759_at 1459870_x_at	20434	-1.032	-0.4257	Yes
79	FRAP1	1417592_at 1436267_a_at 1446185_at 1459625_at	20462	-1.039	-0.4148	Yes
80	EBI3	1449222_at	20514	-1.053	-0.4048	Yes
81	CD4	1419696_at 1427779_a_at	20765	-1.140	-0.4029	Yes
82	TRAF6	1421376_at 1421377_at 1435350_at 1443288_at 1446940_at 1446977_at	20770	-1.143	-0.3898	Yes
83	IL6ST	1421239_at 1437303_at 1452843_at 1460295_s_at	20813	-1.163	-0.3781	Yes
84	STAT3	1424272_at 1426587_a_at 1459961_a_at 1460700_at	20902	-1.208	-0.3680	Yes
85	ATF2	1426582_at 1426583_at 1427559_a_at 1437777_at 1452116_s_at 1459237_at	20910	-1.212	-0.3541	Yes
86	IKBKG	1421208_at 1421209_s_at 1435646_at 1435647_at 1450161_at 1454690_at	20996	-1.253	-0.3434	Yes
87	CREBBP	1434633_at 1435224_at 1436983_at 1444856_at 1457641_at 1459804_at	21006	-1.257	-0.3291	Yes
88	STAT2	1421911_at 1450403_at	21181	-1.359	-0.3212	Yes
89	GADD45G	1453851_a_at	21192	-1.365	-0.3057	Yes
90	ETV5	1420998_at 1428142_at 1450082_s_at	21313	-1.468	-0.2940	Yes
91	MAPK14	1416703_at 1416704_at 1426104_at 1442364_at 1451927_a_at 1459617_at	21320	-1.472	-0.2771	Yes
92	IL2RG	1416295_a_at 1416296_at	21451	-1.604	-0.2643	Yes
93	PRF1	1451862_a_at	21549	-1.718	-0.2487	Yes
94	ARRB2	1426239_s_at 1451987_at	21574	-1.756	-0.2292	Yes
95	IRF1	1448436_a_at	21686	-2.021	-0.2107	Yes
96	GADD45B	1420197_at 1449773_s_at 1450971_at	21794	-2.532	-0.1860	Yes
97	IL1R1	1448950_at 1459777_at	21838	-2.908	-0.1540	Yes
98	RELB	1417856_at	21846	-2.947	-0.1198	Yes
99	IL27RA	1449508_at	21882	-3.395	-0.0818	Yes
100	BCL3	1418133_at	21891	-3.545	-0.0407	Yes
101	FOS	1423100_at	21901	-3.644	0.0015	Yes